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Molecular Metabolism 2025

Nutrient control of splice site selection contributes to methionine addiction of cancer

Cancer Research 2023

Role of PP2A methylation on methionine dependence of cancer

Submitted 2025

Sphingosine and anti-neoplastic sphingosine analogs activate PP2A and inhibit nuclear import in parallel by engaging PPP2R1A and importins

Cell Chem. Biol. 2022

Discovery of compounds that reactivate p53 mutants in vitro and in vivo

J Lipid Res. 2021

Lipid remodeling in response to methionine stress in MDA-MBA-468 triple-negative breast cancer cells

J. Biol. Chem. 2019

Microhomology based CRISPR tagging tools for protein tracking, purification, and depletion

Methods Mol. Biol. 2019

Isolation and Characterization of Methionine-Independent Clones from Methionine-Dependent Cancer Cells

J. Cell. Sci. 2014

S-adenosylmethionine limitation induces p38 mitogen activated protein kinase and triggers cell cycle arrest in G1

Nature Communications. 2013

Computational Identification of a Transiently Open L1/S3 Pocket for p53 Cancer Mutant Reactivation.

Cell Cycle. 2012

Downregulation of Cdc6 and pre-replication complexes in response to methionine stress in breast cancer cells.

J. Biol. Chem. 2008

Transforming growth factor β up-regulates cysteine-rich protein 2 in vascular smooth muscle cells via activating transcription factor 2

Genes to Cells. 2008

Identification of a putative human mitochondrial thymidine monophosphate kinase associated with monocytic/macrophage terminal differentiation

U.S. Patent 2015

Chembridge Small Molecules that could enhance p53 activity

This Next Publication is coming soon!

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Take a Chance!

“IN THE END… We only regret the chances we didn’t take, the relationships we were afraid to have,and the decisions we waited too long to make.” ― Lewis Carroll

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